Aziz Denian, M.D. Denian during his fellowship training with Professor Brandstater at the Stroke Management Unit, Loma Linda University Hospital, California, in 2003. Aziz Denian, M.D., currently runs the Denian Clinic, a private practice for neurorehabilitation, pain management and mesotheraphy services in Amman, Jordan. The neurorehabilitation program is a combination of neurological and behavioral assessment, followed by treatment with a medicinal and/or brain stimulation series designed to alleviate the effects of pain or memory loss. The clinic's mesotherapy program provides therapies to improve skin abnormalities and imperfections due to aging and/or disease. Currently, Denian is investigating methods to stimulate brain regeneration, particularly in Alzheimer's and post-traumatic brain injuries. Denian received his M.D. from Yerevan Medical School, Armenia, in 1985. From 1985-2007, Denian worked for the Royal Medical Services of Jordan as a Consultant in Neurorehabilitiation, Pain and Antiaging Medicine. He received the Clinical and Research Fellowship in General & Neurological Rehabilitation Medicine from Loma Linda University Medical School in 2003- 2004, and presented his work in the 2003 annual meeting of the Association of Academic Psychiatrists. Denian began training courses in mesotheraphy at Bordeaux II University, France in 2005, and he resigned from his position at Royal Medical Services to open the Denian Clinic in 2007. Denian receives his Mesotherapy Certificate with Professor Petit (France) and Professor Silva (Argentina) from Bordeaux II University, France, 2004. Occupation and research interests Currently, I am successfully practicing aesthetic mesotherapy to treat wrinkles, lines, stretch marks and cellulite. Additionally, I am practicing therapeutic mesotherapy for neuro-musculoskeletal regenerative conditions and pain management. At the same time I am reestablishing my scientific investigations by self-proposed methods to stimulate brain regeneration in cases of Alzheimer's and post-traumatic brain injuries, with preliminary but promising results. Also, I am investigating the improvement of injection methods in blocking headaches by peri-scalp and peripheral feedback subcutaneous injections (mixtures consisting of FDA approved medications). I am planning to re-introduce low frequency electromagnetic fields to my practice in parallel. My research involves pathologies related to amnesia, dementia and other cognitive acquired defects. Current brain stimulation and renormalization with the available knowledge remains generalized with the neural and vascular components within the brain. What were your motivations in pursuing the clinical side of neuroregenerative therapies? While being at Loma Linda University, California, for my fellowship training, I participated in the academic and research activities with Professor Murray Brandstater and colleagues. I worked at the adult and child spasticity clinics and pain management clinics with surgical pain management invasive injections, neuro-blocking procedures, pain-spasticity implanted electronic pumps, Botox and other blockers. I was trained on the management of stroke and traumatic brain injuries, therapies for cerebral palsy patients, and on using the medications within these fields. I participated at the electrophysiological clinics where I enrolled in the preparation of two clinical studies on spasticity and coagulation in stroke, and was actively involved in a spasticity study on TBI. During this time I realized my capabilities in the medical sciences and I realized the possibilities of achieving a breakthrough in medical science. Professor Murray Brandstater's approach for his patients and his dedication for his work and science influenced me in my practice, and influenced me to utilize my scientific potential. What are a few short term goals in your clinical practice? I have practiced medicine since 1985. My current work at my private clinic does not limit my potential; it gives me more time for thinking, studying and to work on becoming more creative. The methods I am using consist of minimally invasive medication mixtures injected subcutaneously and intradermaly in specific distributions. I am planning to arrange for other medical technologies in parallel to my injection methods and smart medications for the stimulation and normalization of the diseased brain, as well as for the treatment of multiple types of headaches. I will be designing a lab budget to study the outcome of my clinical management at the cellular, chemical and pharmacological levels, in the near future. This is essential so as to understand and explain my current and upcoming progress in the clinical improvement of my CNS and PNS diseased patients. In regards to future developments, what type of neuroregenerative breakthroughs do you predict? Brain regeneration studies are still in the headlines. Almost all the available antagonists, blockers, stimulators and suppressors are being studied; in memory, complex gate coordination and control, muscle tone, behaviors, etc. I don’t think that a specific treatment would solve a single or a couple of the brain defective functions, at least in the near future. I can predict in what I believe, and what I predict is what we could do right now, until the opportunities for specific treatments become more likely. Currently, I predict that brain stimulation by external factors such as renormalization, plus stimulating the auto- regenerative and metabolic mechanisms such as with the targeted surface injections, and using the smart group medications, to smoothly stimulate the brain circulation and enhancement of the neural cell metabolism, is so far the most comprehensive combination available. Currently, I have preliminary but promising clinical results. I have some achievements in accelerating the healing of locked-in patients, and accelerating some localized (isolated) motor improvements in TBI and stroke. For headaches, I am achieving tremendous results in the treatment of my patients, both with migraines and cluster and tension headaches. I have many patients with prolonged remissions as long as six months and with very mild relapses thereafter. Finally, the question that I am frequently asking myself is this: “I am able with my injections to interfere and alleviate a migraine for a few months, which is a vascular and chemically mediated pathological condition. Therefore, I should be able with the same technique, in use with other technologies, to interfere and correct more specific vascular and metabolic dysfunctions of the brain. Could I interfere with the degenerative process? At this point, I think that a multidisciplinary research team, surrounded with the best available technology, is mandatory for further achievements. -------------------------------------------------------------------------------------------------------------------------------------------------------- To discuss clinical neurology and other topics with fellow Science Advisory Board members, please visit our community forum. Weblinks Dr. Denian's Clinic This is a website for Denian's patients to gather more information on services offered and Denian's professional experience and publications. Mesotherapy Center This website is a work in progress, and will feature the details of an upcoming Mesotheraphy Center. Dr Denian's Publications Exploration Of “DenianTMD”. Previously unknown and unclassified type of Temporomandibular joint dysfunction TMD associated and predisposed by the systemic hypermobility syndrome SHMS, Pan Arab Medical Journal, Vol 2. No 10. October- December 2007. Civil War Amputees In Sierra Leone. A Prospective survey study on 145 survived amputee patients. Screening the levels, and predicting the demand for proper re-evaluation, and Ortho- Neuro- Psychological comprehensive rehabilitation program. Pan Arab Medical Journal, Vol 2. No 8. Jan-March 2007, P57-63. Local corticosteroid injections in the management of Pes-Anserine Bursitis, Prospective clinical study, Jordan Medical Journal, Vol 37. No 2. Nov 2003. TMD due to muscle hyperlaxety. “Hypermobility syndrome” new case series recently presented during the Association Of Academic Physiatrists 2003 Annual Meeting/Fort Lauderdale, Florida, March 27-29, 2003. American Journal of Physical Medicine & Rehabilitation, Vol. 82. March 2003 # 3 p250. Confirmation of the Median nerve entrapment at the carpal tunnel, Carpal tunnel syndrome "CTS", by the Nerve conduction study " NCS", Review of 144 patients. Journal Of The Royal Medical Services Dec-1999. |
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| Aziz Denian, MD. Science Advisory Bord Member Since 2002 |
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Dr. Denian's Clinic
MD. Senior Consultant
Neuro Esthetic, Pain And Anti Aging Rehab.
Professional Rehabilitation & Cell Regeneration Medical Services
MD. Senior Consultant
Neuro Esthetic, Pain And Anti Aging Rehab.
Professional Rehabilitation & Cell Regeneration Medical Services
| Al-Khalidi Medical Plaza, Iben-Khaldoon Street, Jabal Amman, Jordan. 00962 (0)79 6444578 |
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